Resources · Article · January 2026

Lensless SPR, Better Data,
and a Transatlantic Adventure.

A US patent, a precision kinetics case study, and the carry-on test — three things that happened this month.

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US Patent Granted for Lensless SPR.

The US Patent Office has granted Affinité Instruments a patent for our lensless SPR architecture — the core innovation that makes our instruments compact, affordable, and genuinely different from everything else on the market.

US Patent Granted Lensless Surface Plasmon Resonance — no optical components, no alignment, no tradeoffs

Traditional SPR systems rely on precise optical alignment — lenses, prisms, and complex mechanics that add size, cost, and fragility. Our architecture achieves the same measurement by eliminating the lens entirely. The result: a smaller instrument, a simpler workflow, and a path to miniaturization that conventional optics simply can't follow.

"Simplicity here isn't a compromise — it's a consequence of getting the physics right."
Patented lensless SPR technology — Affinité Instruments

This patent protects the foundation of everything we build — and sets the stage for the next generation of instruments that will extend lensless SPR to workflows that have never been accessible before.

See the instruments →

Precision Antibody Kinetics with the P4PRO.

We ran a Protein A–IgG binding assay on the P4PRO to show what flow-controlled SPR delivers when everything is dialled in. AffiCoat sensors with reference channels. AffiPump fluidics for stable, reproducible flow. Kinetics fitting that matches published literature values — with better curve quality than expected.

AffiCoat sensors
Reference channels included — non-specific binding subtracted automatically.
AffiPump fluidics
Stable, controlled flow — clean association and dissociation phases, every run.
Under two hours
From surface prep to fitted kinetic constants — including regeneration cycles.
P4PRO sensorgram — Protein A–IgG association and dissociation phases P4PRO kinetics fitting — kon, koff, KD results
"Kinetic constants matching literature values — with superior data fitting. Achievable results, directly on your bench, in under two hours."

The full application note walks through the surface preparation, injection protocol, and fitting approach — with all raw data and parameters included.

Read the application note → Explore the P4PRO →

The Carry-On Test.

We packed a P4PRO into a carry-on. Checked it in, flew across the Atlantic, unpacked it at the destination. Powered it on. Ran a binding assay.

It worked. Flawlessly.

Ludovic with the P4PRO packed for transatlantic travel
"Powerful SPR can also be compact, robust, and deliver high-quality kinetic data directly to your bench — wherever that bench happens to be."

The P4PRO fits in a carry-on. Our service model fits your schedule. Whether you're running experiments in your home lab or setting up at a collaborator's site — the instrument travels with you, and it's ready when you are.

Book a conversation →