Every publication. One platform.
Browse the full list of peer-reviewed publications, book chapters, and preprints from labs worldwide — filterable by topic and searchable by keyword.
Browse publications →The lensless optical architecture isn't just what makes our instruments smaller. It's the cornerstone of the translational biosensing platform we're building.
How a patented optical foundation enables miniaturization, workflow integration, a path to automation, and signal quality you can trust — and why those are all consequences of the same design decision.
Read the technical note →Your Sensorgram Is Telling You Something.
We've traveled to labs on four continents. The most common thing we hear: "I'm not sure my data is good enough." Here's how to read what your sensorgram is actually saying.
Read the guide →Decoding SPR Sensorgrams
A visual reference for the most common sensorgram shapes — ideal binding, bulk RI shifts, baseline drift, non-specific binding, slow dissociation and more.
Open cheat sheet →Surface Chemistry Explained
Understand the two immobilization strategies — direct covalent coupling vs. capture-based — and which one fits your experiment.
Decoding SPR Sensorgrams
Quick visual reference for diagnosing common SPR data issues at a glance.
Gene Regulation — DNA-Protein Binding
Characterising the LacI–LacO interaction using the P4SPR in a label-free format.
Environmental Field Testing — RDX Detection
Real-world detection of explosive residues in water using portable SPR biosensing.
Protein–Small Molecule Binding
Pheromone–CD36 transmembrane protein binding characterised by SPR with sub-μM KD values.
Assay Optimization — Immunosensing
Oriented His-tag immobilization yields 5–10× greater surface density and superior reproducibility for anti-EcAII detection in patient serum.
QC of Antibodies — SARS-CoV-2
Rapid label-free quality control of antibody preparations — activity and purity in one run.
Protein–Protein Interaction Screening
Rapid, label-free mapping of EntA–F biosynthetic pathway interactions using the P4SPR quad-channel platform.
Monitoring AAV Bioproduction with SPR
Real-time SPR monitoring of AAV capsid binding during gene therapy vector production.
Covalent Immobilisation of Proteins
Step-by-step EDC/NHS coupling protocol for immobilising proteins on P4SPR sensor chips.
Metal Chelation Immobilisation
His-tag capture via NTA–Ni²⁺ for oriented protein immobilisation on SPR surfaces.
Online Streptavidin Capture
Biotinylated ligand capture using pre-coated streptavidin sensor chips for kinetic analysis.
Static vs. Flow-Based SPR
Comparing static incubation and flow-controlled injection modes — when to use each and why.
Sensors & Surface Chemistry
Overview of available sensor surfaces, self-assembled monolayers, and surface chemistry options.
Understanding the Sensorgram
A technical breakdown of sensorgram anatomy — phases, units, fitting models and common artefacts.
Issue 7 — Your Sensorgram Is Telling You Something.
Field notes from four continents, sensorgram diagnostics, and what we're building next.
A Simple SPR Solution for Complex Samples
PEGS 2025 · Zhao S., Ricard P., Meredith R., Campbell C., Live L. — mAb characterization during biomanufacturing and IgG1–Protein A kinetics with the P4SPR.